Apomorphine Subcutaneous Injection for the Management of Morning Akinesia in Parkinson's Disease
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چکیده
منابع مشابه
Apomorphine Subcutaneous Injection for the Management of Morning Akinesia in Parkinson's Disease
BACKGROUND In patients with motor fluctuations complicating Parkinson's disease (PD), delays in time-to-ON with levodopa are common. This open-label study aimed to assess the effect of apomorphine on time-to-ON in PD patients with morning akinesia. METHODS The safety population included 127 enrolled patients, and the full analysis set (FAS) included 88 patients. Patients completed a 7-day lev...
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[Subcutaneous apomorphine in the treatment of Parkinson's disease].
Motor and psychiatric complications are the main limitations for chronic treatment with levodopa in patients with Parkinson's disease (PD). Apomorphine (APM) is a potent D1 and D2 dopaminergic agonist that has been proven useful in the management of PD. Ten patients with complicated PD involving fluctuations in mobility and dyskinesia were treated with subcutaneous APM (1 with continuous infusi...
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ژورنال
عنوان ژورنال: Movement Disorders Clinical Practice
سال: 2016
ISSN: 2330-1619
DOI: 10.1002/mdc3.12350